Structure of PDB 8tpt Chain A

Receptor sequence
>8tptA (length=579) Species: 660122 (Fusarium vanettenii 77-13-4) [Search protein sequence]
SNFGVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLL
VFVKVSPDLFAKQVYRARLGDWLHGVRVEAERLRLIYLMITKPHNEGGAG
VTPTNAKWKHVESIFPLHSHSFNKEWIKKWSSKYTLEQTDIDNIRDKFGE
SVAFYFAFLRSYFRFLVIPSAFGFGAWLLLGQFSYLYALLCGLWSVVFFE
YWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAKVYPPMKRVKTQLLQI
PFALACVVALGALIVTCNSLEVFINEVYSGPQYLGFLPTIFLVIGTPTIS
GVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNFMTSYMALFFTAFVYI
PFGHILHPFLNFWRINPARISNQMFYFTVTPQIVNFATEVVVPYIKQQAF
EEAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWPLAACCFLV
NNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLSWLGSITSSAIV
YLCSNAWGLLLSILFAEHFYLVVQLAVRFVLSKLPGLQKERKERFQTKKR
LLTPEEMFWQRQRGMQETIEIGRRMIEQQ
3D structure
PDB8tpt Structural basis of closed groove scrambling by a TMEM16 protein.
ChainA
Resolution3.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E452 D503 E506 E535 D539 E389 D423 E426 E455 D459
BS02 CA A N448 E452 E506 E535 N385 E389 E426 E455
BS03 PGW A S566 W570 S486 W490
BS04 PGW A F375 F379 P560 T563 F567 F331 F335 P480 T483 F487
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0032541 cortical endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tpt, PDBe:8tpt, PDBj:8tpt
PDBsum8tpt
PubMed38684930
UniProtC7Z7K1

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