Structure of PDB 8tps Chain A

Receptor sequence
>8tpsA (length=588) Species: 660122 (Fusarium vanettenii 77-13-4) [Search protein sequence]
SNFGVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLL
VFVKVSPDLFAKQVYRARLGDWLHGVRVSAPHNDIAQALQEPVVEAERLR
LIYLMITKPHNEGGAGVTPTNAKWKHVESIFPLHSHSFNKEWIKKWSSKY
TLEQTDIDNIRDKFGESVAFYFAFLRSYFRFLVIPSAFGFGAWLLLGQFS
YLYALLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEA
KVYPPMKRVKTQLLQIPFALACVVALGALIVTCNSLEVFINEVYSGPQYL
GFLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLN
FMTSYMALFFTAFVYIPFGHILHPFLNFWRINPARISNQMFYFTVTPQIV
NFATEVVVEEAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWP
LAACCFLVNNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLSWLG
SITSSAIVYLCSNAWGLLLSILFAEHFYLVVQLAVRFVLSKLDSPGLQKE
RKERFQTKKRLLPEEMFWQRQRGMQETIEIGRRMIEQQ
3D structure
PDB8tps Structural basis of closed groove scrambling by a TMEM16 protein.
ChainA
Resolution2.97 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D503 E506 E535 D539 D431 E434 E463 D467
BS02 PGW A T563 S566 W570 T491 S494 W498
BS03 PGW A F375 F379 P560 F567 F347 F351 P488 F495
BS04 PGW A V615 L618 V530 L533
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0032541 cortical endoplasmic reticulum

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8tps, PDBe:8tps, PDBj:8tps
PDBsum8tps
PubMed38684930
UniProtC7Z7K1

[Back to BioLiP]