Structure of PDB 8tlo Chain A

Receptor sequence
>8tloA (length=85) Species: 9606 (Homo sapiens) [Search protein sequence]
SDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMK
THGQVGKDVYKCEICKMPFSVYSTLEKHMKKWHSD
3D structure
PDB8tlo Crystal Structure Analysis of BCL11A in complex with DNA
ChainA
Resolution2.76 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A K752 N756 Y777 Q781 K784 R787 H788 T791 V811 T814 K12 N16 Y37 Q41 K44 R47 H48 T51 V71 T74
BS02 dna A N753 S755 S783 N13 S15 S43
BS03 ZN A C744 H760 H764 C4 H20 H24
BS04 ZN A C772 H788 H792 C32 H48 H52
BS05 ZN A C802 C805 H818 H823 C62 C65 H78 H83
External links
PDB RCSB:8tlo, PDBe:8tlo, PDBj:8tlo
PDBsum8tlo
PubMed
UniProtQ9H165|BC11A_HUMAN B-cell lymphoma/leukemia 11A (Gene Name=BCL11A)

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