Structure of PDB 8tlk Chain A

Receptor sequence
>8tlkA (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
GSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDT
KTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCS
FCRQR
3D structure
PDB8tlk The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
ChainA
Resolution2.99 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A G231 T234 L235 S257 R258 R264 T269 R274 Q275 K276 D288 W290 G291 V292 G1 T4 L5 S27 R28 R34 T39 R44 Q45 K46 D58 W60 G61 V62
BS02 ZN A C270 C273 C297 C300 C40 C43 C67 C70
BS03 ZN A H271 C327 C329 C332 H41 C97 C99 C102
BS04 ZN A C284 C289 C320 C323 C54 C59 C90 C93
External links
PDB RCSB:8tlk, PDBe:8tlk, PDBj:8tlk
PDBsum8tlk
PubMed38168392
UniProtQ9BWT1|CDCA7_HUMAN Cell division cycle-associated protein 7 (Gene Name=CDCA7)

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