Structure of PDB 8tlg Chain A

Receptor sequence
>8tlgA (length=103) Species: 10090 (Mus musculus) [Search protein sequence]
MTLPHIIRPVEEVTEEEIRNICSNSREKIYNRSLGSTCHQCRQKTTDTKT
NCRNPDCWGIRGQFCGPCLRNRYGEEVKDALLDPNWHCPPCRGICNCSFC
RQR
3D structure
PDB8tlg The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
ChainA
Resolution2.09 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T245 S268 R269 R275 T280 R285 Q286 K287 D299 W301 G302 I303 T2 S25 R26 R32 T37 R42 Q43 K44 D56 W58 G59 I60
BS02 ZN A C281 C284 C308 C311 C38 C41 C65 C68
BS03 ZN A H282 C338 C340 C343 H39 C95 C97 C100
BS04 ZN A C295 C300 C331 C334 C52 C57 C88 C91
External links
PDB RCSB:8tlg, PDBe:8tlg, PDBj:8tlg
PDBsum8tlg
PubMed38168392
UniProtQ9D0M2|CDCA7_MOUSE Cell division cycle-associated protein 7 (Gene Name=Cdca7)

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