Structure of PDB 8tjb Chain A

Receptor sequence
>8tjbA (length=317) Species: 1980844 (Influenza A virus (A/Texas/73/2017(H3N2))) [Search protein sequence]
PGATLCLGHHAVPNGTIVKTITNDRIEVTNATELVQNSSIGEICDSPHQI
LDGENCTLIDALLGDPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYASL
RSLVASSGTLEFKNESFNWTGVTQNGKSSACIRRSSSSFFSRLNWLTHLN
YTYPALNVTMPNKEQFDKLYIWGVHHPGTDKDQIFLYAQSSGRITVSTKR
SQQAVIPNIGSRPRIRDIPSRISIYWTIVKPGDILLINSTGNLIAPRGYF
KIRSGKSSIMRSDAPIGKCKSECITPNGSIPNDKPFQNVNRITYGACPRY
VKHSTLKLATGMRNVPE
3D structure
PDB8tjb Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
ChainA
Resolution2.45 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y98 K135 S136 S137 W153 L194 I226 S228 Y90 K127 S128 S129 W145 L186 I218 S220
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8tjb, PDBe:8tjb, PDBj:8tjb
PDBsum8tjb
PubMed38307019
UniProtA0A1W6AW68

[Back to BioLiP]