Structure of PDB 8tj9 Chain A

Receptor sequence
>8tj9A (length=317) Species: 1731408 (Influenza A virus (A/Michigan/15/2014(H3N2))) [Search protein sequence]
PGATLCLGHHAVPNGTIVKTITNDRIEVTNATELVQNSSIGEICDSPHQI
LDGENCTLIDALLGDPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYASL
RSLVASSGTLEFNNESFNWTGVTQNGTSSACIRRSSSSFFSRLNWLTHLN
YKYPALNVTMPNNEQFDKLYIWGVHHPGTDKDQIFLYAQSSGRITVSTKR
SQQAVIPNIGSRPKIRDIPSRISIYWTIVKPGDILLINSTGNLIAPRGYF
KIRSGKSSIMRSDAPIGKCKSECITPNGSIPNDKPFQNVNRITYGACPRY
VKHSTLKLATGMRNVPE
3D structure
PDB8tj9 Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y98 T135 S136 S137 W153 L194 I226 S228 Y90 T127 S128 S129 W145 L186 I218 S220
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tj9, PDBe:8tj9, PDBj:8tj9
PDBsum8tj9
PubMed38307019
UniProtA0A0Y0S9M3

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