Structure of PDB 8tj8 Chain A

Receptor sequence
>8tj8A (length=317) Species: 480019 (Influenza A virus (A/Moscow/10/1999(H3N2))) [Search protein sequence]
PGATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDSPHQI
LDGENCTLIDALLGDPHCDGFQNKEWDLFVERSKAYSNCYPYDVPDYASL
RSLVASSGTLEFNNESFNWTGVAQNGTSSACKRRSINSFFSRLNWLHQLK
YRYPALNVTMPNNDKFDKLYIWGVHHPSTDSDQTSLYTQASGRVTVSTKR
SQQTVIPNIGSRPWVRGISSRISIYWTIVKPGDILLINSTGNLIAPRGYF
KIRSGKSSIMRSDAPIGKCNSECITPNGSIPNDKPFQNVNRITYGACPRY
VKQNTLKLATGMRNVPE
3D structure
PDB8tj8 Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
ChainA
Resolution2.56 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y98 T135 S136 S137 W153 L194 Y90 T127 S128 S129 W145 L186
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tj8, PDBe:8tj8, PDBj:8tj8
PDBsum8tj8
PubMed38307019
UniProtI6SI59

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