Structure of PDB 8tj7 Chain A

Receptor sequence
>8tj7A (length=317) Species: 1144025 (Influenza A virus (A/Shandong/9/1993(H3N2))) [Search protein sequence]
PGATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICGSPHRI
LDGKNCTLIDALLGDPHCDGFQNKEWDLFVERSKAYSNCYPYDVPDYASL
RSLVASSGTLEFINEDFNWTGVAQDGGSYACKRGSVNSFFSRLNWLHKLE
YKYPALNVTMPNNGKFDKLYIWGVHHPSTDSDQTSLYVRASGRVTVSTKR
SQQTVTPNIGSRPWVRGQSSRISIYWTIVKPGDILLINSTGNLIAPRGYF
KIRNGKSSIMRSDAPIGNCSSECITPNGSIPNDKPFQNVNRITYGACPRY
VKQNTLKLATGMRNVPE
3D structure
PDB8tj7 Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
ChainA
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y98 G135 S136 Y137 H183 L194 S228 Y90 G127 S128 Y129 H175 L186 S220
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tj7, PDBe:8tj7, PDBj:8tj7
PDBsum8tj7
PubMed38307019
UniProtH9XM74

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