Structure of PDB 8tj6 Chain A

Receptor sequence
>8tj6A (length=317) Species: 380949 (Influenza A virus (A/Beijing/353/1989(H3N2))) [Search protein sequence]
PGATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDSPHRI
LDGKNCTLIDALLGDPHCDGFQNKEWDLFVERSKAYSNCYPYDVPDYASL
RSLVASSGTLEFINEDFNWTGVAQSGESYACKRGSVKSFFSRLNWLHESE
YKYPALNVTMPNNGKFDKLYIWGVHHPSTDREQTNLYVRASGRVTVSTKR
SQQTVIPNIGSRPWVRGLSSRISIYWTIVKPGDILLINSTGNLIAPRGYF
KIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNRITYGACPRY
VKQNTLKLATGMRNVPE
3D structure
PDB8tj6 Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
ChainA
Resolution2.85 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y98 G134 E135 S136 Y137 W153 H155 H183 E190 L194 Y90 G126 E127 S128 Y129 W145 H147 H175 E182 L186
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8tj6, PDBe:8tj6, PDBj:8tj6
PDBsum8tj6
PubMed38307019
UniProtO11283|HEMA_I89A2 Hemagglutinin (Gene Name=HA)

[Back to BioLiP]