Structure of PDB 8tj4 Chain A

Receptor sequence
>8tj4A (length=317) Species: 385630 (Influenza A virus (A/Bangkok/1/1979(H3N2))) [Search protein sequence]
PGATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDSPHRI
LDGKNCTLIDALLGDPHCDGFQNEKWDLFVERSKAFSNCYPYDVPDYASL
RSLVASSGTLEFINEGFNWTGVTQSGGSYACKRGSDNSFFSRLNWLYESE
SKYPVLNVTMPNNGNFDKLYIWGVHHPSTDKEQTNLYVRASGRVTVSTKR
SQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDILLINSNGNLIAPRGYF
KIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYGACPKY
VKQNTLKLATGMRNVPE
3D structure
PDB8tj4 Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y98 G135 S136 Y137 W153 H183 E190 L194 S228 Y90 G127 S128 Y129 W145 H175 E182 L186 S220
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tj4, PDBe:8tj4, PDBj:8tj4
PDBsum8tj4
PubMed38307019
UniProtP03441|HEMA_I79A0 Hemagglutinin (Fragment) (Gene Name=HA)

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