Structure of PDB 8th7 Chain A

Receptor sequence
>8th7A (length=134) Species: 9606 (Homo sapiens) [Search protein sequence]
EKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDGKPADAV
YGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQAL
RRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFG
3D structure
PDB8th7 Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
ChainA
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L10 V11 E14 F15 R17 Q18 Q25 H31 R32 F33 Q58 K59 N122 K123 F124 Y125 L7 V8 E11 F12 R14 Q15 Q22 H28 R29 F30 Q53 K54 N117 K118 F119 Y120
External links
PDB RCSB:8th7, PDBe:8th7, PDBj:8th7
PDBsum8th7
PubMed38492217
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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