Structure of PDB 8th1 Chain A

Receptor sequence
>8th1A (length=137) Species: 9606 (Homo sapiens) [Search protein sequence]
VMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKP
ADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNN
NQALRRFMQTFVLAPEGVANKFYVHNDIFRYQDEVFG
3D structure
PDB8th1 Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A F15 Q18 R32 F33 N122 K123 F124 Y125 F14 Q17 R31 F32 N120 K121 F122 Y123
External links
PDB RCSB:8th1, PDBe:8th1, PDBj:8th1
PDBsum8th1
PubMed38492217
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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