Structure of PDB 8tfy Chain A

Receptor sequence
>8tfyA (length=177) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
SRFKVSKLMAYILRHSPWEFGLEPDEEGFVSIEELVNAVRKVYPWVTEEY
IREIVERDEKGRYEIRGNKIRARYGHSYPVILRHEEDKESKVLYHGTVRR
NLKGIMREGIKPMKRQYVHLSINYEDAYNTGMRHGEDVVVLIIDAECLRN
KGYKILKAGKKVRIVKHVPVDCISGIL
3D structure
PDB8tfy Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.
ChainA
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A S6 K7 A10 R14 K60 R62 Y74 R133 S6 K7 A10 R14 K60 R62 Y74 R133
Gene Ontology
Molecular Function
GO:0000215 tRNA 2'-phosphotransferase activity
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation

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Molecular Function
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Biological Process
External links
PDB RCSB:8tfy, PDBe:8tfy, PDBj:8tfy
PDBsum8tfy
PubMed37883434
UniProtO57899|KPTA_PYRHO Probable RNA 2'-phosphotransferase (Gene Name=kptA)

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