Structure of PDB 8tec Chain A

Receptor sequence
>8tecA (length=448) Species: 10090 (Mus musculus) [Search protein sequence]
VPRGSGTENLYFQGHMALDGIRMPDGCYADGTWELSVHVTDLNRDVTLRV
TGEVHIGGVMLKLVEKLDVKKDWSDHALWWEKKRTWLLKTHWTLDKCGIQ
ADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHP
EELSLLKKPRPLSPPGILAVSQPVTSPEILAKMFKPQALLDKAKTNQGWL
DSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWALL
LEEIECTEEEMMMFAALQYHINKLSIMTSENHLTTDVNPECLVSPRYLKK
YKSKQITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQG
GKREELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFA
DEVRLSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTS
3D structure
PDB8tec Acetyl-NPKY of integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
ChainA
Resolution2.04 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F609 S610 M612 K613 Q614 W615 N616 V617 N618 W619 I654 L675 S677 F380 S381 M383 K384 Q385 W386 N387 V388 N389 W390 I425 L446 S448
External links
PDB RCSB:8tec, PDBe:8tec, PDBj:8tec
PDBsum8tec
PubMed38904068
UniProtQ8CIB5|FERM2_MOUSE Fermitin family homolog 2 (Gene Name=Fermt2)

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