Structure of PDB 8tdh Chain A

Receptor sequence

>8tdhA (length=451) Species: 239759 (Alistipes) [Search protein sequence]

DKLNILGVGIGGRGSSVLRGLESQNIIGLCDVDWKYADHVFKRYPAAKKY
NDYRKMFDEMLKSADAVMVATADHTHAIIAADAMTAGKHVYVEKPLTHTV
YESRLLTKLADKYKVATQMGNQGASDEGVRKVCEWIWNGEIGEVRKVETF
TDRPIWPQGLSRPEDDQRIPKTLNWDAFIGPAPYRPYNAIYTPWNFRGWW
DFGTGALGDMACHILHPVFKGLKLGYPTKVQGSSTLLLNESAPMAQTVKF
VFPARDNMPKVAMPEVEVYWYDGGLKPARPEGLPAGKDLNMAGGGVIFYG
TKDTLICGCYGVNPYLVSGRVPNAPKVLREIKESHQMDWVRACKEDADDR
VPSASDFSEAGPFNEMVVMGVLAVRLQNLNRELLWDGPNMRFTNIPDDAT
ISAVIKDGFHIKDGHPTFDKTWTDPVNAQQFAQELIKHTYRDGWKLPDMP
R

3D structure

PDB

8tdh An alternative broad-specificity pathway for glycan breakdown in bacteria.

Chain

Resolution

2.95 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	GLC	A	R192 D248 H252 Y349	R153 D209 H213 Y310
BS02	GLC	A	R184 Y338	R145 Y299
BS03	GLC	A	T462 D463 V465	T423 D424 V426
BS04	GLC	A	D240 N278 R414	D201 N239 R375
BS05	GLC	A	A125 G126 K127	A86 G87 K88
BS06	NAD	A	G48 G50 G51 R52 D70 V71 Y75 A109 T110 D112 H115 E132 K133 Q161 F217 W233 F235 R236 H252	G9 G11 G12 R13 D31 V32 Y36 A70 T71 D73 H76 E93 K94 Q122 F178 W194 F196 R197 H213

External links

PDB	RCSB:8tdh, PDBe:8tdh, PDBj:8tdh
PDBsum	8tdh
PubMed	38898276

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