Structure of PDB 8tcc Chain A

Receptor sequence
>8tccA (length=232) Species: 28450 (Burkholderia pseudomallei) [Search protein sequence]
QMPIQRVGVRAVRHPLTVRTQATVGTWNLDVHLPADQKGTHMSRFVALLE
ERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVSLLD
YEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQHNQRSHVTIDAELA
ADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDV
ARRLDDERIVAYVLEAENFEHNHSAYALIERD
3D structure
PDB8tcc Combatting melioidosis with chemical synthetic lethality
ChainA
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A C154 H166 C128 H137
BS02 SO3 A E250 H253 E220 H221
Gene Ontology
Molecular Function
GO:0003933 GTP cyclohydrolase activity
GO:0003934 GTP cyclohydrolase I activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0046654 tetrahydrofolate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8tcc, PDBe:8tcc, PDBj:8tcc
PDBsum8tcc
PubMed
UniProtA0A069BB45

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