Structure of PDB 8tav Chain A

Receptor sequence
>8tavA (length=241) Species: 1385527 (Staphylococcus aureus USA300-0114) [Search protein sequence]
LPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHA
APPDEILKSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSL
NRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKDQETIDNEMDH
FKPTETLKELSEALDTIKEQVDEVLDPILVIQAENDNMIDPQSANYIYDH
VDSDDKNIKWYSESGHVITIDKEKEQVFEDIYQFLESLDWS
3D structure
PDB8tav FphH, Staphylococcus aureus fluorophosphonate-binding serine hydrolases H, boronic acid-based compound N34 bound
ChainA
Resolution1.39 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZKR A F24 S93 P117 A125 I126 H220 F20 S89 P113 A121 I122 H216
BS02 ZKR A F66 F69 K101 A167 T170 F62 F65 K97 A163 T166
BS03 ZKR A F66 F69 L73 N105 F62 F65 L69 N101
BS04 CA A D206 D208 D202 D204
BS05 CA A D149 D153 D145 D149
Gene Ontology
Molecular Function
GO:0016298 lipase activity
GO:0016787 hydrolase activity
GO:0106435 carboxylesterase activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8tav, PDBe:8tav, PDBj:8tav
PDBsum8tav
PubMed
UniProtQ2G025

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