Structure of PDB 8t94 Chain A

Receptor sequence
>8t94A (length=178) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
SAMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMY
SDFGKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFI
EIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESR
ARIKTRLFTIRQEMASRSLWDSFRQSER
3D structure
PDB8t94 Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants.
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A H41 D108 E119 I120 H43 D90 E101 I102
BS02 MN A E80 D108 E62 D90
BS03 IJM A K34 A37 I38 H41 E80 D108 E119 K134 R196 K36 A39 I40 H43 E62 D90 E101 K116 R178
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:8t94, PDBe:8t94, PDBj:8t94
PDBsum8t94
PubMed38190441
UniProtC3W5S0

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