Structure of PDB 8t88 Chain A

Receptor sequence
>8t88A (length=277) Species: 1385527 (Staphylococcus aureus USA300-0114) [Search protein sequence]
GMETLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVV
AVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYI
LGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVH
QILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWLE
FEIRQYTHSNITLDDFTKYSDKITLLNGTDSRGSFPQDVNFYINKETGIP
IVDIPGGHLGYIQKPEGFADVLLNMWG
3D structure
PDB8t88 Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections.
ChainA
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YW0 A A28 S103 P129 A29 S104 P130
BS02 YW0 A T153 L156 E157 M160 F163 L167 M177 Q190 Y191 T194 W197 H257 T154 L157 E158 M161 F164 L168 M178 Q191 Y192 T195 W198 H258
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0017171 serine hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:8t88, PDBe:8t88, PDBj:8t88
PDBsum8t88
PubMed38411555
UniProtQ2FDS6|Y2518_STAA3 Uncharacterized hydrolase SAUSA300_2518 (Gene Name=SAUSA300_2518)

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