Structure of PDB 8t85 Chain A

Receptor sequence
>8t85A (length=335) Species: 562 (Escherichia coli) [Search protein sequence]
QPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTP
DLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAA
AAKLLQELQPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYC
LDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPELGALLKQVNHLL
RQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVPLG
TLGNAYLNQLSQRCDAWQCQIWGTGGRLRLMLSAE
3D structure
PDB8t85 Structure of phosphorylated-like RssB, the adaptor delivering sigma s to the ClpXP proteolytic machinery, reveals an interface switch for activation.
ChainA
Resolution2.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D15 D58 A60 D13 D56 A58
BS02 BEF A D58 I59 A60 S86 A87 K108 D56 I57 A58 S84 A85 K106
Gene Ontology
Molecular Function
GO:0000156 phosphorelay response regulator activity
GO:0000976 transcription cis-regulatory region binding
GO:0005515 protein binding
GO:0016989 sigma factor antagonist activity
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:0031648 protein destabilization
GO:0045862 positive regulation of proteolysis
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol
GO:0032993 protein-DNA complex
GO:1903865 sigma factor antagonist complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8t85, PDBe:8t85, PDBj:8t85
PDBsum8t85
PubMed37949227
UniProtP0AEV1|RSSB_ECOLI Regulator of RpoS (Gene Name=rssB)

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