Structure of PDB 8t81 Chain A

Receptor sequence
>8t81A (length=174) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
SAMEDFVRQCFNPMIVELAEKAMKKYGEDPKIETNKFAAICTHLEVCFMY
SDFHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEI
GVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRAR
IKTRLFTIRQEMASRSLWDSFRQS
3D structure
PDB8t81 Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants.
ChainA
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A H41 D108 E119 I120 H43 D88 E99 I100
BS02 MN A E80 D108 E60 D88
BS03 IJM A K34 A37 I38 H41 D108 E119 K134 K36 A39 I40 H43 D88 E99 K114
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8t81, PDBe:8t81, PDBj:8t81
PDBsum8t81
PubMed38190441
UniProtC3W5S0

[Back to BioLiP]