Structure of PDB 8t7v Chain A

Receptor sequence
>8t7vA (length=310) Species: 9606 (Homo sapiens) [Search protein sequence]
KPYEKVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWIC
SENLSLQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPL
EVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNY
ESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSK
EMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKNHKVIPVYVGVNIKGLHLL
NMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
LLMKLNGQLM
3D structure
PDB8t7v Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZTA A Q473 K475 V512 K720 L721 K724 Q57 K59 V96 K300 L301 K304
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8t7v, PDBe:8t7v, PDBj:8t7v
PDBsum8t7v
PubMed37974623
UniProtO00522|KRIT1_HUMAN Krev interaction trapped protein 1 (Gene Name=KRIT1)

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