Structure of PDB 8t7p Chain A

Receptor sequence

>8t7pA (length=884) Species: 5833 (Plasmodium falciparum) [Search protein sequence]

PKIHYRKDYKPSGFIINQVTLNINIHDQETIVRSVLDMDISKHNVGEDLV
FDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVI
IHPETNYALTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTA
DKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPPLKPCYLFAVVAGDLKHL
SATYITKYTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYD
LSRLNLVAVSDFNVGASENKGLNIFNANSLLASKKNSIDFSYARILTVVG
HEYFHQYTGNRVLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHVDL
LRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTILGE
EYYKKGFDIYIKKNATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSG
TPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVGLINPEN
GKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDQLTDEE
RILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESFQLTPVN
AQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLDTDVLADTKE
YIYKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNMRTLRNT
LLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSLSVSAYFDKYFELYDKTY
KLSKDDELLLQEWLKTVSRSDRKDIYEILKKLENEVLKDSKNPNDIRAVY
LPFTNNLRRFHDISGKGYKLIAEVITKTDKFNPMVATQLCEPFKLWNKLD
TKRQELMLNEMNTMLQEPQISNNLKEYLLRLTNK

3D structure

PDB

8t7p Conformational dynamics of the Plasmodium falciparum M1 aminopeptidase.

Chain

Resolution

2.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	A	H496 H500 E519	H301 H305 E323

External links

PDB	RCSB:8t7p, PDBe:8t7p, PDBj:8t7p
PDBsum	8t7p
PubMed
UniProt	O96935\|AMPN_PLAF7 Aminopeptidase N (Gene Name=M1AAP)

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