Structure of PDB 8t5v Chain A

Receptor sequence

>8t5vA (length=178) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]

SAMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFVAICTHLEVCFMY
SDFGRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEI
GVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRAR
IKTRLFTIRQEMASRSLWDSFRQSERGE

3D structure

PDB

8t5v Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants.

Chain

Resolution

1.79 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	MN	A	H41 D108 E119 I120	H43 D88 E99 I100
BS02	MN	A	E80 D108	E60 D88
BS03	E4Z	A	Y24 E26 K34 A37 I38 H41 E80 D108 E119 K134	Y26 E28 K36 A39 I40 H43 E60 D88 E99 K114

External links

PDB	RCSB:8t5v, PDBe:8t5v, PDBj:8t5v
PDBsum	8t5v
PubMed	38190441
UniProt	C3W5S0

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