Structure of PDB 8t5a Chain A

Receptor sequence
>8t5aA (length=132) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAHFLLKLA
GRWPVKTVHTDNGSNFTSTTVKTACWWAGIKQSMNKELKKIIGQVRDQAE
HLKTAVQMAVFIHNHKRYSAGERIVDIIATDI
3D structure
PDB8t5a The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
ChainA
Resolution1.93 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 WBV A A169 E170 H171 T174 A99 E100 H101 T104
External links
PDB RCSB:8t5a, PDBe:8t5a, PDBj:8t5a
PDBsum8t5a
PubMed38328097
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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