Structure of PDB 8t52 Chain A

Receptor sequence
>8t52A (length=132) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAHFLLKLA
GRWPVKTVHTDNGSNFTSTTVKTACWWAGIKQSMNKELKKIIGQVRDQAE
HLKTAVQMAVFIHNHKRYSAGERIVDIIATDI
3D structure
PDB8t52 The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
ChainA
Resolution2.07 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 QD6 A A169 E170 H171 T174 A99 E100 H101 T104
External links
PDB RCSB:8t52, PDBe:8t52, PDBj:8t52
PDBsum8t52
PubMed38328097
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

[Back to BioLiP]