Structure of PDB 8t51 Chain A

Receptor sequence
>8t51A (length=215) Species: 9606 (Homo sapiens) [Search protein sequence]
EVQLVESGGGLVQPGGSLKLSCATSGFPFSNVWMHWVRQASGKGLEWIAH
IKAKSDNYATYYAESVKGRFTISRDDSKTTIYLQMNSLKTEDTAVYYCTG
LDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEP
VTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVN
HKPSNTKVDKKVEPK
3D structure
PDB8t51 Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining
ChainA
Resolution1.9 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A V2 F27 P28 N31 V32 W33 D102 Y103 V2 F27 P28 N31 V32 W33 D102 Y103
External links