Structure of PDB 8t3l Chain A

Receptor sequence
>8t3lA (length=303) Species: 10116 (Rattus norvegicus) [Search protein sequence]
LSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRI
FYFNFFVYCLYMIIFTAAAYYRPLPPYKLKNTVGDYFRVTGEILSVSGGV
YFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKE
YVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLV
FLFGFSTAVVTLIEDGKYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTE
KSF
3D structure
PDB8t3l Structural basis of TRPV1 modulation by endogenous bioactive lipids.
ChainA
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8IJ A D509 S510 Y511 S512 L515 T550 L553 Y554 E570 I696 Q700 D123 S124 Y125 S126 L129 T164 L167 Y168 E184 I287 Q291
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8t3l, PDBe:8t3l, PDBj:8t3l
PDBsum8t3l
PubMed38698206
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

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