Structure of PDB 8t2j Chain A

Receptor sequence
>8t2jA (length=339) Species: 9606 (Homo sapiens) [Search protein sequence]
MAGLYSLRVSVFSDQGGRKYMEDVTQIVVEPEETAERSSVAFFAVCDGHG
GREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLA
EWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDKDDFVRA
VEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPALTHNGPVAAS
TVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYII
LGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQ
RMLRADNTSAIVICISPEVDNTNEDELYLNLTDSPSYNS
3D structure
PDB8t2j Structure of the catalytic domain of PPM1D/Wip1 serine/threonine phosphatase
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D105 G106 D47 G48
BS02 MG A D105 D314 D366 D47 D254 D306
External links
PDB RCSB:8t2j, PDBe:8t2j, PDBj:8t2j
PDBsum8t2j
PubMed39002674
UniProtO15297|PPM1D_HUMAN Protein phosphatase 1D (Gene Name=PPM1D)

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