Structure of PDB 8t1o Chain A

Receptor sequence
>8t1oA (length=599) Species: 10090 (Mus musculus) [Search protein sequence]
GMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKY
VCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSEL
IRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAG
DTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAAT
SLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLS
VKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNA
VLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLAS
SEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAE
MLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVS
EEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFG
NLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKAT
IQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPG
3D structure
PDB8t1o Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PIO A R11 G12 K57 K61 R3 G4 K49 K53
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0030117 membrane coat
GO:0030121 AP-1 adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8t1o, PDBe:8t1o, PDBj:8t1o
PDBsum8t1o
PubMed37364761
UniProtP17427|AP2A2_MOUSE AP-2 complex subunit alpha-2 (Gene Name=Ap2a2)

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