Structure of PDB 8t03 Chain A

Receptor sequence
>8t03A (length=199) Species: 10090 (Mus musculus) [Search protein sequence]
VAKLLLPTLSSLAFLPTVSIATKRRFYMEAMVYLFTMFFVAFSHACDGPG
LSVLCFMRRDILEYFSIYGTALSMWVSLMALADFDEPQRSTFTMLGVLTI
AVRTFHDRWGYGVYSGPIGTATLIIAVKWLKKMKEKKGLYPDKSIYTQQI
GPGLCFGALALMLRFFFEEWDYTYVHSFYHCALAMSFVLLLPKVNKKAG
3D structure
PDB8t03 Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
ChainA
Resolution2.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H48 H180 H184 H44 H176 H180
BS02 CLR A W79 L99 T103 R107 G116 G120 T124 W75 L95 T99 R103 G112 G116 T120
BS03 LBN A M78 W113 Y115 G116 Y118 S119 G161 F191 M74 W109 Y111 G112 Y114 S115 G157 F187
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0007517 muscle organ development
GO:0007520 myoblast fusion
GO:0014905 myoblast fusion involved in skeletal muscle regeneration
GO:0043403 skeletal muscle tissue regeneration
GO:0045026 plasma membrane fusion
GO:1904206 positive regulation of skeletal muscle hypertrophy
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8t03, PDBe:8t03, PDBj:8t03
PDBsum8t03
PubMed37770716
UniProtQ9D1N4|MYMK_MOUSE Protein myomaker (Gene Name=Mymk)

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