Structure of PDB 8szu Chain A

Receptor sequence
>8szuA (length=366) Species: 470 (Acinetobacter baumannii) [Search protein sequence]
GHMKKIGYVWDTLYSWVDTGTNLSKRIQPITHHMNHPDTKRRFNELVMTS
GQIDFLTPIKPYPATDADILRVHDKQLLDNAKNVSNKECGGDIGDRVTHL
GNGGIEIAYLSAGGAIELTKKVISGELHTGYALVSPPGHHATKKDSMGFC
IFNNTSIAAAYAKDILGLKRVAIVDWDVHHGNGTQDIWWEDSSVLTISIH
QNKCFPTNSGFINERGAGNGFGYNLNIPLPPGSGNGAYIYAFEKVIVPAL
KKYEPELIIVGSGFDASILDPLSRMMVSSEGFKKMASLILEVSNEINGGK
CLFVQEGGYSPHYLPFCGLAVIEALTGMHTLDDPLIDMVGEMGGNELLPH
EKKVVDECANLIADIN
3D structure
PDB8szu Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii .
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 X4U A I31 I34 V101 H143 H144 F153 D181 H183 F209 Y313 I27 I30 V97 H139 H140 F149 D177 H179 F205 Y309
BS02 X4U A L273 M342 M346 L269 M338 M342
BS03 ZN A D181 H183 D269 D177 H179 D265
BS04 X4U A H316 L339 H312 L335
Gene Ontology
Molecular Function
GO:0004407 histone deacetylase activity
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006338 chromatin remodeling
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8szu, PDBe:8szu, PDBj:8szu
PDBsum8szu
PubMed37624144
UniProtR8YPJ7

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