Structure of PDB 8szr Chain A

Receptor sequence
>8szrA (length=856) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
EPYKVNLSQDLEHQLQNIIQELNLEIVPPPDDPFMPVVLNLGKPSQRQNQ
MGVVPWSPPQSNWNPWTSSNIDEGPLAYATPEQISMDLKNELMYQLEQDH
DLPAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFIL
DDFIQNDRAAECNIVVTQPRRISAVSVAERVAYERGEEPGKSCGYSVRFE
SVLPRPYASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVV
LRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLE
DCIQMTHFIPPDANCNLICGDEYGPETKMSMAQLNEKETPFELIEALLKY
IETLNVPGAVLVFLPGWNLIYTMQKHLEMNPDFGSHRYQILPLHSQIPRE
EQRKVFDPVPAGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHN
NMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEM
FRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALD
ANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTISAATCFPEPF
ISEGKRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHK
RLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVVIS
LLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFF
VFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVLVDDWIRLQIS
HEAAACITALRAAMEALVVEVTKQPNIISQLDPVNEHMLNMIRQISRPSA
AGINLM
3D structure
PDB8szr Crystal structures of DExH-box RNA helicase DHX9
ChainA
Resolution2.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A T414 G415 G417 K418 T419 T420 R457 F700 T722 T137 G138 G140 K141 T142 T143 R180 F406 T428
BS02 MG A T419 E513 T142 E236
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0033679 3'-5' DNA/RNA helicase activity

View graph for
Molecular Function
External links
PDB RCSB:8szr, PDBe:8szr, PDBj:8szr
PDBsum8szr
PubMed37860960
UniProtA0A8I3RTG4

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