Structure of PDB 8szq Chain A

Receptor sequence
>8szqA (length=861) Species: 9685 (Felis catus) [Search protein sequence]
ETVEPYKVNLSQDLEHQLQNVIQELNLEIVPPPEDPFLPVVLNLGSQRQN
QIGVVPWSPPQSNWNPWTSSNIDEGPLAYATPEQISMDLKNELMYQLEQD
HDLQAILQERELLPVKKFESEILEAISQNSVIIIRGATGCGKTTQVPQFI
LDDFIQNDRAAECNIVVTQPRRISAVSVAERVAYERGEEPGKSCGYSVRF
ESVLPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLV
VLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFL
EDCIQMTHFVPPPDANCNLICGDEYGPETRMSMAQLNEKETPFELIEALL
KYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGSHRYQILPLHSQIP
REEQRKVFDPVPSGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTA
HNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTP
EMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDA
LDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTISAATCFPE
PFISEGKRLGYVHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCE
HKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVV
ISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSP
FFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVLVDDWIRLQ
ISHEAAACITALRAAMEALVVEVTKQPNIISQLDPVNEHMLNMIRQISRP
SAAGINLMIDY
3D structure
PDB8szq Crystal structures of DExH-box RNA helicase DHX9
ChainA
Resolution2.711 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A T414 G415 G417 K418 T419 T420 R457 F700 T722 T138 G139 G141 K142 T143 T144 R181 F408 T430
BS02 MG A T419 E513 T143 E237
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0033679 3'-5' DNA/RNA helicase activity

View graph for
Molecular Function
External links
PDB RCSB:8szq, PDBe:8szq, PDBj:8szq
PDBsum8szq
PubMed37860960
UniProtM3WPI7

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