Structure of PDB 8sy0 Chain A

Receptor sequence
>8sy0A (length=358) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
WVKILSVVGARPQFIKAAAVSRVLRASPGVREVLVHTGQHYDDNMSQVFF
EELEIPDPDYHLGIGGGTHGQNTGRMLEAIEGVLLKEKPDWVLVYGDTDS
TLAGALAAVKLHIPVAHVEAGLRSFNRRMPEEINRILTDHASDLLFAPTE
TAVQNLLREGIPENRIHLVGDVMYDAALHYGAKAERKSRILERLGLQAKG
YVLATIHRAENTDDQERLRVILEALAEVHQEVPVVFPVHPRTRKRAEAFG
LGSYLEKVVALEPVGYLDMVMLEKNARLIVTDSGGVQKEAYFYRVPCVTV
REETEWVELLKAEWNYLAAPQNAKDLALTILHRMRTKGVEIDLYGDGRAS
QKISDFLR
3D structure
PDB8sy0 Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.1.3.14: UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MJ3 A R12 P13 Q14 I16 K17 F50 G97 D98 E120 E132 H208 V265 Y267 M270 S284 G285 G286 E290 W307 R11 P12 Q13 I15 K16 F49 G96 D97 E119 E131 H207 V264 Y266 M269 S283 G284 G285 E289 W306
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity
GO:0016853 isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:8sy0, PDBe:8sy0, PDBj:8sy0
PDBsum8sy0
PubMed37660908
UniProtQ72KY0

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