Structure of PDB 8sxg Chain A

Receptor sequence
>8sxgA (length=366) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SAPLPLDELRTFAEVLDRVKAAYVEPVDDKTLLENAIKGMLSNLDPHSAY
LGPEDFAELQESTSGEFGGLGIEVGSEDGFIKVVSPIDDTPAARAGIQPG
DLIVQIDGKPTKGQSMTEAVDSMRGKAGSPITLTIVRDGGRPFDVELKRA
IIKVKSVKSQVLEPGYAYLRITQFQVNTGEEVVKALNQLRKDNKGRLKGL
VLDLRNNPGGVLQSAVEVADAFLTKGLIVYTKGRIANSELRFSADPADPS
DKVPLVVLINGGSAAAAEIVAGALQDQKRAILMGTDSFGKGSVQTVLPLN
NDRALKLTTALYYTPNGRSIQAQGIVPDIEVGRAKVTQESERPQDSDYQL
SQALSLLKGLSVTRGN
3D structure
PDB8sxg P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process
ChainA
Resolution4.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G247 A302 K327 Q331 G210 A265 K290 Q294
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0030254 protein secretion by the type III secretion system
GO:0042546 cell wall biogenesis
GO:0043163 cell envelope organization
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0030313 cell envelope
GO:0042597 periplasmic space

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Molecular Function
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Cellular Component
External links
PDB RCSB:8sxg, PDBe:8sxg, PDBj:8sxg
PDBsum8sxg
PubMed38467832
UniProtQ9HU50

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