Structure of PDB 8sxb Chain A

Receptor sequence
>8sxbA (length=1152) Species: 9915 (Bos indicus) [Search protein sequence]
SVLPEDRSQHLGEELQGYWDQEVLRAEKDAREPSLTKAIIKCYWKSYVVL
GIFTLIEESTRVVQPIILGKIIGYFENYDPSDSAALYEAHGYAGVLSACT
LVLAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNSAMGKTTTGQIV
NLLSNDVNKFDQVTIFLHFLWAGPLQAIVVTALLWMEIGISCLAGMAVLI
ILLPLQSCIGKLFSSLRSKTAAFTDTRIRTMNEVITGIRIIKMYAWEKSF
ADLITNLRRKEISKILRSSYLRGMNLASFFVASKIIVFVTFTTYVFLGNV
ITASRVFVAVSLYGAVRLTVTLFFPSAVEKVSEAFVSIRRIKNFLLLDEI
VNVQDFTAFWDKASDTPTLQSLSFTVRPGELLAVVGPVGAGKSSLLSAVL
GELPPNQGQVSVHGRIAYVSQQPWVFSGTVRSNILFGKKYEKERYEKVIK
ACALKKDLQLLEDGDLTMIGDRGTTLSGGQKARVNLARAVYQDADIYLLD
DPLSAVDAEVSRHLFELCICQALHEKIRILVTHQLQYLKAASQILILKDG
QMVQKGEGKVGFKAYKNYFTAGAHWFIIIFLILVNLAAQVSYILQDWWLS
YWANQQSALTEKLDLNWYLGIYSGLTASTVLFGIVRSLLVFFVLVSSSQT
LHNQMFESILRAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTYLDFIQT
FLQVIGVVGVAVAVIPWIAIPLVPLGIVFFVLRRYFLETSRDVKRLESTT
RSPVFSHLSSSLQGLWTIRAYKAEQRFQELFDSHQDLHSEAWFLFLTTSR
WFAVRLDAICAVFVIVVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWC
VRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPLPSWPHEGVIIFDNV
NFSYSLDGPLVLKHLTALIKSKEKVGIVGRTGAGKSSLIAALFRLSEPEG
KIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHSDEEL
WNALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNR
ILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMV
LDSGRLKEYDEPYVLLQNRDSLFYKMVQQLGKAEAAALTETAKQVYFKRN
YP
3D structure
PDB8sxb Structural basis of prostaglandin efflux by MRP4.
ChainA
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P2E A D2162 T2166 R2266 W2315 R2318 D696 T700 R800 W849 R852
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8sxb, PDBe:8sxb, PDBj:8sxb
PDBsum8sxb
PubMed38216659
UniProtA0A6P5CNW8

[Back to BioLiP]