Structure of PDB 8sx8 Chain A

Receptor sequence
>8sx8A (length=1175) Species: 9913 (Bos taurus) [Search protein sequence]
FFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGYWDQEVLRAE
KDAREPSLTKAIIKCYWKSYVVLGIFTLIEESTRVVQPIILGKIIGYFEN
YDPSDSAALYEAHGYAGVLSACTLVLAILHHLYFYHVQCAGMRLRVAMCH
MIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQA
IVVTALLWMEIGISCLAGMAVLIILLPLQSCIGKLFSSLRSKTAAFTDTR
IRTMNEVITGIRIIKMYAWEKSFADLITNLRRKEISKILRSSYLRGMNLA
SFFVASKIIVFVTFTTYVFLGNVITASRVFVAVSLYGAVRLTVTLFFPSA
VEKVSEAFVSIRRIKNFLLLDEIVNVQDFTAFWDKASDTPTLQSLSFTVR
PGELLAVVGPVGAGKSSLLSAVLGELPPNQGQVSVHGRIAYVSQQPWVFS
GTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTMIGDRGTTLS
GGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQALHEKI
RILVTHQLQYLKAASQILILKDGQMVQKGEGKVGFKAYKNYFTAGAHWFI
IIFLILVNLAAQVSYILQDWWLSYWANQQSALTEKLDLNWYLGIYSGLTA
STVLFGIVRSLLVFFVLVSSSQTLHNQMFESILRAPVLFFDRNPIGRILN
RFSKDIGHMDDLLPLTYLDFIQTFLQVIGVVGVAVAVIPWIAIPLVPLGI
VFFVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEQRF
QELFDSHQDLHSEAWFLFLTTSRWFAVRLDAICAVFVIVVAFGSLILAKT
LDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEA
PWEYQKRPLPSWPHEGVIIFDNVNFSYSLDGPLVLKHLTALIKSKEKVGI
VGRTGAGKSSLIAALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQE
PVLFTGTMRKNLDPFNEHSDEELWNALEEVQLKEAIEDLPGKMDTELAES
GSNFSVGQRQLVCLARAILRKNRILIIDEATANVDPRTDELIQKKIREKF
AHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNRDSLFYKMV
QQLGKAEAAALTETAKQVYFKRNYP
3D structure
PDB8sx8 Structural basis of prostaglandin efflux by MRP4.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XPG A H152 F324 D842 R946 Q994 W995 R998 H130 F302 D719 R823 Q871 W872 R875
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8sx8, PDBe:8sx8, PDBj:8sx8
PDBsum8sx8
PubMed38216659
UniProtF1MUC1

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