Structure of PDB 8swz Chain A

Receptor sequence
>8swzA (length=248) Species: 9606 (Homo sapiens) [Search protein sequence]
SEQLQALLLEEVMNSSTLSQEVSDLVEMIWAEALGHLEHMLGSPNPPSLA
KYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRVNET
TEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLG
SGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEA
PPGYDSVHGVSQTASVTTDFEDDEFVVYKTNQVKMKYIIKFSMPGDQI
3D structure
PDB8swz Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UHB A H438 G439 S440 N444 G447 I448 G452 L453 L454 Y477 Y488 H115 G116 S117 N121 G124 I125 G129 L130 L131 Y154 Y165
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:8swz, PDBe:8swz, PDBj:8swz
PDBsum8swz
PubMed37971310
UniProtQ9UKK3|PARP4_HUMAN Protein mono-ADP-ribosyltransferase PARP4 (Gene Name=PARP4)

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