Structure of PDB 8swq Chain A

Receptor sequence
>8swqA (length=302) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence]
DINEQRALIKSAHRYISEKLEDHFSSEFLPKALVICGSGLSGISTKIADE
PKPLILSYSTIPGFKVSTVPGHSGELIFGYMNGAPVVLMNGRLHSYEGHS
LAETVHPIRALHLLGSINVLIVTNAAGGINASFKAGDLMCVYDHINFPGL
CGFHPLRGANFDEFGPRFLATSDAYDLELRKLLFSKKKELNIERKIHEGT
YSYVHGPTFESRAESRFLRLAGTDAVGMSTVPEVVTARHCGWRVLALSLI
TNECVVDPPASAHDENPVPIQEGKATHEEVLENSAKASKDVQELIFSVVA
EI
3D structure
PDB8swq Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity.
ChainA
Resolution1.979 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.1: purine-nucleoside phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DIH A A129 A130 G131 F213 E214 M232 N256 H281 V284 A125 A126 G127 F209 E210 M228 N252 H277 V280
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004731 purine-nucleoside phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009116 nucleoside metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8swq, PDBe:8swq, PDBj:8swq
PDBsum8swq
PubMed37812583
UniProtQ6CSZ6

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