Structure of PDB 8swb Chain A

Receptor sequence
>8swbA (length=149) Species: 9606 (Homo sapiens) [Search protein sequence]
GDFVVVYTDGCCSSNGRRRPRAGIGVYWGPGHPLNVGIRLPGRQTNQRAE
IHAACKAIEQAKTQNINKLVLYTNSMFTINGITNWVQGWKKNGWKTSAGK
EVINKEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSE
3D structure
PDB8swb Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A C147 C148 S150 N151 R153 N182 Q183 E186 N210 M212 H260 C11 C12 S14 N15 R17 N46 Q47 E50 N74 M76 H124
BS02 rna A N151 G152 T181 N182 Q183 F213 W221 W225 T232 S233 V238 I239 N240 N15 G16 T45 N46 Q47 F77 W85 W89 T96 S97 V102 I103 N104
External links
PDB RCSB:8swb, PDBe:8swb, PDBj:8swb
PDBsum8swb
PubMed
UniProtO60930|RNH1_HUMAN Ribonuclease H1 (Gene Name=RNASEH1)

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