Structure of PDB 8spp Chain A

Receptor sequence
>8sppA (length=368) Species: 1893 (Streptomyces atratus) [Search protein sequence]
DPLFSPLDPAVLADPYPVYRRLRETHPVYWHAGLDSWLMTRHADCTAILR
DPGRFSTDFRKIDIPTPPTLLSLQTLDPPDQTPLRHLALDAVRAQDLDAL
RKELTLFADQLLDELADRESFDFIHDYADVFTLRAITRFIGVEPPETDEA
FARFNEPGLRARAHFNDLVRSWLGDPGPHGVLPDVVRLLPGSGVEADDVL
VNSVRAFFHAGFEVPSRFLGNALAALLATPGAWEQLVRGDVGLDTAVEEL
IRYVGPVQALARACLQDTELGGMAVKEGQVVTALIGAANRDPDQFPDPET
LRLDRKPNNHLGFGRGAHSCLGLNVARIEAHVTLGALLRHPGVRSAGEPV
VRPNGTLRGLSRLPLTLG
3D structure
PDB8spp Structural and spectroscopic characterization of RufO indicates a new biological role in rufomycin biosynthesis.
ChainA
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A L83 R95 F233 A236 G237 V240 F244 L286 R288 G338 F339 H344 C346 G348 A352 L73 R85 F207 A210 G211 V214 F218 L260 R262 G312 F313 H318 C320 G322 A326
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0008395 steroid hydroxylase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0036199 cholest-4-en-3-one 26-monooxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0006707 cholesterol catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8spp, PDBe:8spp, PDBj:8spp
PDBsum8spp
PubMed37451485
UniProtA0A224AU14

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