Structure of PDB 8slw Chain A

Receptor sequence
>8slwA (length=921) Species: 10116 (Rattus norvegicus) [Search protein sequence]
CKGEVNFKRSKFVKVPSNVAPSMLFELLLTEWHLPAPNLVVSLVGEERLF
AMKSWLRDVLRKGLVKAAQSTGAWILTSALHVGLARHVGQAVRDHSLAVR
VVAIGMASLDRILHRQLLDGTPIHYPADLCPLDSNLSHFILVLAELQLSL
EKHISQQRTGSSIQIPVLCLLVNGDPSTLERMSRAVEQAAPWLILAGSGG
IADVLAALVGQPHLLVPQVTEKQFREKFPSECFSWEAIVHWTELLQNIAA
HPHLLTVYDFEQEGSEDLDTVILKALVKACKSHSRDAQDYLDELKLAVAW
DRVDIAKSEIFNGDVEWKSCDLEEVMTDALVSNKPDFVRLFVDSGADMAE
FLTYGRLQQLYHSVSPKSLLFELLERKHEEGRLLPAFSLHEVSRVLKDFL
HDACRGFYQDWLPDLSRKSEDPWRDLFLWAVLQNRYEMATYFWAMGREGV
AAALAACKIIKEMSHLEKEAEVARTMREAKYEQLALDLFSECYSNSEDRA
FALLVRRNHSWSRTTCLHLATEADAKAFFAHDGVQAFLTKIWWGDMATGT
PILRLLGAFTCPALIYTNLISFSEAAFLLTRWRKFWGAPVTVFLGNVVMY
FAFLFLFSYVLLVDFRPPPQGPSGSEVTLYFWVFTLVLEEIRQGFFTDTR
LVKKFTLYVEDNWNKCDMVAIFLFIVGVTCRMVPSVFEAGRTVLAIDFMV
FTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLVAYGVTTQAL
LHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDEARVANWLVILLLVTFL
LVTNVLLMNLLIAMFSYTFQVVQGNADMFWKFQRYHLIVEYHGRPALAPP
FILLSHLSLVLKQVFRHLERDLPDPVDQKIITWETVQKENFLSTMEKRRR
DSEEEVLRKTAHRVDLIAKYI
3D structure
PDB8slw Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
ChainA
Resolution4.2 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A Q225 D350 D353 E354 Q164 D289 D292 E293
BS02 CA A E781 Q784 E1002 E640 Q643 E840
External links