Structure of PDB 8sgs Chain A

Receptor sequence
>8sgsA (length=381) Species: 9606 (Homo sapiens) [Search protein sequence]
SVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLL
AMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKF
GSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLN
GTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPMPTPGLTLGKKEDK
LGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQAL
GIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWR
AAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAER
HYRDARITEIYEGTSEIQRLVIAGHLLRSYR
3D structure
PDB8sgs High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.
ChainA
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.8.1: short-chain acyl-CoA dehydrogenase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003995 acyl-CoA dehydrogenase activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0016937 short-chain fatty acyl-CoA dehydrogenase activity
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0046359 butyrate catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005813 centrosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8sgs, PDBe:8sgs, PDBj:8sgs
PDBsum8sgs
PubMed37839702
UniProtP16219|ACADS_HUMAN Short-chain specific acyl-CoA dehydrogenase, mitochondrial (Gene Name=ACADS)

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