Structure of PDB 8sgj Chain A

Receptor sequence
>8sgjA (length=751) Species: 9606 (Homo sapiens) [Search protein sequence]
SYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMS
SIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILL
SVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHL
RVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWV
ADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPPVSKIFFEQGTYQCLENC
GTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQ
KEIRVGIIDDDIFEEDENFLVHLSNVKVSSTLACLGSPSTATVTIFDDDH
AGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGE
DFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSE
KKALLLNELGGFTITGKYLFGQPVFRKVHAREHPILSTVITIAPLTSKEE
EERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNSWREQFIEA
ITSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIG
DLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGN
VTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAF
INVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCH
I
3D structure
PDB8sgj Structural mechanisms of human cardiac sodium calcium exchanger NCX1
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0005432 calcium:sodium antiporter activity
Biological Process
GO:0006816 calcium ion transport
GO:0007154 cell communication
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8sgj, PDBe:8sgj, PDBj:8sgj
PDBsum8sgj
PubMed37794011
UniProtP32418|NAC1_HUMAN Sodium/calcium exchanger 1 (Gene Name=SLC8A1)

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