Structure of PDB 8s9u Chain A

Receptor sequence

>8s9uA (length=768) Species: 1148 (Synechocystis sp. PCC 6803) [Search protein sequence]

MRGIEITITMQSDWHVGTGMGRGELDSVVQRDGDNLPYIPGKTLTGILRD
SCEQVALGLDNGQTRGLWHGWINFIFGDQPALAQGAIEPEPRPALIAIGS
AHLDPKLKAAFQGKKQLQEAIAFMKPGVAIDAITGTAKKDFLRFEEVVRL
GAKLTAEVELNLPDNLSETNKKVIAGILASGAKLTERLGGKRRRGNGRCE
LKFSGYSDQQIQWLKDNYQSVDQPPKYQQNKLQSAGDNPEQQPPWHIIPL
TIKTLSPVVLPARTVGNVVECLDYIPGRYLLGYIHKTLGEYFDVSQAIAA
GDLIITNATIKIDGKAGRATPFCLFGEKLDGGLGKGKGVYNRFQESEPDG
IQLKGERGGYVGQFEQEQRNLPNTGKINSELFTHNTIQDDVQRPTSDVGG
VYSYEAIIAGQTFVAELRLPDSLVKQITSKNKNWQAQLKATIRIGQSKKD
QYGKIEVTSGNSADLPKPTGNNKTLSIWFLSDILLRGDRLNFNATPDDLK
KYLENALDIKLKERSDNDLICIALRSQRTESWQVRWGLPRPSLVGWQAGS
CLIYDIESGTVNAEKLQELMITGIGDRCTEGYGQIGFNDPLLSASLGKLT
AKNPLPTNHPTQDYARLIEKAAWREAIQNKALALASSRAKREEILGIKIM
GKDSQPTMTQLGGFRSVLKRLHSRNNRDIVTGYLTALEQVSNRKEKWSNT
SQGLTKIRNLVTQENLIWNHLDIDFSPLTITQNGVNQLKSELWAEAVRTL
VDAIIRGHKRDLEKAQEN

3D structure

PDB

8s9u Type III CRISPR-Cas effectors act as protein-assisted ribozymes

Chain

Resolution

2.77 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	G17 T18 T43 G46 R49 D50 D78 Q79 P80 P93 A94 V128 A129 I130 T136 F141 L142 R143 G189 G190 K191 R192 R193 R194 P261 R278 Y279 H285 S295 I298 H384 N385 T386 I387 Q392 R393 P394 Y402 I444 G445 S447 K448 K449 W532 Q533 V534 R535 R540 R577 E580	G17 T18 T43 G46 R49 D50 D78 Q79 P80 P93 A94 V128 A129 I130 T136 F141 L142 R143 G189 G190 K191 R192 R193 R194 P261 R278 Y279 H285 S295 I298 H384 N385 T386 I387 Q392 R393 P394 Y402 I444 G445 S447 K448 K449 W532 Q533 V534 R535 R540 R577 E580
BS02	rna	A	D26 K139 D140 F141 L142 R143 F144 T395 S396 G399 G400 V401 T670 T672 Q673 R678 V703 N705 R706 K709 R769 K772	D26 K139 D140 F141 L142 R143 F144 T395 S396 G399 G400 V401 T657 T659 Q660 R665 V690 N692 R693 K696 R756 K759

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Biological Process
GO:0051607	defense response to virus

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8s9u, PDBe:8s9u, PDBj:8s9u
PDBsum	8s9u
PubMed
UniProt	Q6ZED2

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