Structure of PDB 8s7f Chain A

Receptor sequence
>8s7fA (length=231) Species: 562 (Escherichia coli) [Search protein sequence]
ATLFIADLHLCAEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDD
PNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEK
VLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKR
IAARMRANAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQTA
FRVVLGAWHTEGSMVKVTADDVELIHFPFHH
3D structure
PDB8s7f Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors.
ChainA
Resolution1.6 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D8 H10 D41 H197 D7 H9 D40 H186
BS02 MN A D41 N79 H114 H195 D40 N78 H113 H184
BS03 A1H5P A A45 W46 N79 R80 F82 Y125 F128 V132 Q138 F141 M156 R157 A44 W45 N78 R79 F81 Y124 F127 V131 Q137 F140 M155 R156
External links
PDB RCSB:8s7f, PDBe:8s7f, PDBj:8s7f
PDBsum8s7f
PubMed39236497
UniProtQ8FK47|LPXH_ECOL6 UDP-2,3-diacylglucosamine hydrolase (Gene Name=lpxH)

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