Structure of PDB 8s3x Chain A

Receptor sequence
>8s3xA (length=268) Species: 9606 (Homo sapiens) [Search protein sequence]
GEVLGKGFFGQAIKVKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVL
KFIGVLYKDKKLNLLTEYIEGGTLKDFLRSFPWQQKVRFAKGIASGMAYL
HSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVERKKRYTVVGNPYWM
APEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLF
WEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYLGELGI
PLPAELEELDHTVSMQYG
3D structure
PDB8s3x Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
ChainA
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H41 A F342 A345 C365 Y407 I408 T412 L458 D469 F9 A12 C26 Y68 I69 T73 L116 D127
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8s3x, PDBe:8s3x, PDBj:8s3x
PDBsum8s3x
PubMed38669909
UniProtP53671|LIMK2_HUMAN LIM domain kinase 2 (Gene Name=LIMK2)

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