Structure of PDB 8s30 Chain A

Receptor sequence
>8s30A (length=209) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSPNSLMK
KITLLKYFRNYMSEHLLKAGANITLPYLRTWFRTRSAIILHLSNGSVQIN
FFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYA
RTMVDKLLS
3D structure
PDB8s30 PLK1-mediated phosphorylation cascade activates Mis18 complex to ensure centromere inheritance.
ChainA
Resolution1.94 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W414 V415 D416 L490 L491 H538 K540 W42 V43 D44 L116 L117 H155 K157
External links
PDB RCSB:8s30, PDBe:8s30, PDBj:8s30
PDBsum8s30
PubMed39236175
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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